ASCP Medical Laboratory Technician (MLT) Practice Exam

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• Which method is BEST for correlating the severity of hemolytic disease of the fetus and newborn (HDFN)?
• What is the term for a nipple-like protrusion found in certain fungal infections?
• Which analyte level would be affected by a delay in centrifugation?
• When performing a bone marrow analysis, which cell type is typically excluded from the differential?
• What type of immunodeficiency is associated with NK cell dysfunction?
• All of the following are urinalysis findings associated with nephrotic syndrome except:
• In what life cycle stage is Trophozoite the only morphological form present?
• What is the half-life of IgG, and why is this duration significant?
• What type of mold is characterized by producing conidia in chains?
• After an acute myocardial infarction (AMI), when do myoglobin levels return to normal?
• What is the name given to the substitution of an amino acid in the hemoglobin chain?
• What absorption technique is used to remove cold (IgM) antibodies, particularly anti-I specificities?
• What type of bacteria can be directly examined using darkfield microscopy?
• What characteristic is associated with Burkholderia cepacia?
• In adults, what condition is associated with increased levels of alpha-fetoprotein (AFP)?
• What is the method of evaluating fibrinogen levels in heparinized patients?
• What is the term used to describe inadequate blood supply that decreases availability of oxygen to the myocardium?
• What is the primary use of 8-Hydroxyquinoline and CPC reagent?
• Which hemolytic process is primarily facilitated by the spleen?
• What is the recommended duration for a break after every 30 minutes of computer use?
• Which anticoagulant does not cause abnormal thrombin time (TT)?
• Infectious mononucleosis is primarily caused by a pathogen that attaches to which type of cell?
• Oliguria is usually correlated with which condition?
• Which class of antibiotics do -mycins belong to?
• Light chains in immunoglobulins can be of which types?
• How many doses are approximately required to obtain a steady state oscillation for evaluating peak and trough levels?
• What does the blue section of the fire diamond represent?
• What is the stage of viral replication called when the HIV envelope is being acquired and the virus is leaving the host cell?
• Which test is commonly used to evaluate hepatic disease?
• Which type of antibody can cause hemolytic disease of the fetus and newborn (HDFN) in any pregnancy?
• What is the most appropriate method for direct examination of the infectious agent of syphilis?
• Jk(a-b-) red cells are __________ to lysis in 2 M urea.
• Which of the following describes the role of magnesium in enzymatic reactions?
• In medical laboratory testing, high specificity indicates an accurate identification of what?
• The presence of homogentisic acid in urine typically leads to which urine color change?
• Which type of sample should not be refrigerated before transport?
• What organism is associated with an increased risk of contracting pneumonia in AIDS patients?
• A urine test strip that is positive for blood may indicate all of the following except:
• Which amino acid is typically elevated in a patient with maple syrup urine disease?
• What is the appearance of Sporothrix in culture?
• Which virus is typically associated with asymptomatic infection and >20% reactive lymphocytes?
• What is the primary purpose of utilizing fluorescent probes in molecular techniques?
• Obstruction of a blood vessel caused by a stationary blood clot is known as?
• Which marker is associated with diffuse cutaneous scleroderma?
• What is a common effect of prolonged delays in laboratory sample processing?
• What is a characteristic finding in the alpha-2-globulin band during serum protein electrophoresis?
• Which of the following is a common cause of hypomagnesemia?
• What agar type is used for isolating Bordatella pertussis?
• Which protein binds the troponin complex to tropomyosin?
• Reye's syndrome is most commonly associated with the ingestion of which substance?
• What is the best dilution for slightly hazy cerebrospinal fluid (CSF)?
• What is the primary appearance of Flavus Aspergillus species?
• Which two biomarkers are NOT specific to cardiac muscle and may be elevated in patients with injury to other muscles?
• What is considered the last resort treatment for immune thrombocytopenic purpura (ITP)?
• What condition is indicated by a positive indole test?
• What is the term used to describe the appearance of mitotic cells in metaphase with no staining?
• A markedly elevated 5-HIAA determination is presumptive evidence for which condition?
• What mutation is commonly associated with chronic neutrophilic leukemia?
• Which protein appears in the alpha-2-globulin band of serum protein electrophoresis?
• What is the part of an enzyme that is separated from its cofactor called?
• Which blood level will decrease during intravascular hemolysis?
• What is the antibody class associated with paroxysmal cold hemoglobinuria?
• What markers do NK cells express?
• Increased levels of which lipid indicate a higher risk of cardiovascular disease?
• Which disease is screened for in blood donors primarily through questions during the screening process?
• Which factor increases the risk of HbS polymerization?
• What does LD50 represent in toxicology?
• What condition is characterized by the presence of significant protein in the urine?
• Proteolytic enzyme techniques may be useful in identifying which of the following antigen groups?
• Which component is most responsible for the increase in sedimentation rate?
• When evaluating liver function, what would a high level of bilirubin typically indicate?
• Which condition involves the presence of Dohle bodies?
• Which test is essential for detecting patients in the window period of a hepatitis B infection?
• What type of bacteria is known to produce yellow pigment?
• Which factors are associated with the intrinsic pathway of coagulation?
• Which subset of effector lymphocytes is primarily responsible for regulating antibody production?
• What is the most suitable specimen for the isolation of Bordetella pertussis?
• Which of the following conditions is most likely to be indicated by the presence of Scl-70 antibodies?
• Which organism is typically seen in thrush in patients with AIDS?
• Which antigen is known to adsorb onto the red cells of adults?
• Which type of PCR testing uses short primers that are not specifically complementary to a particular sequence of a target DNA?
• Iontophoresis is primarily used in the diagnosis of which disease?
• Which pathway includes factors I, II, V, X, and XIII?
• What is typically weakly expressed or not expressed at all on cord blood cells?
• In capillary specimens, potassium, calcium, and total protein are ___________ compared to venous blood, where glucose is typically _______________.
• The organism Paracoccidioides brasiliensis is associated with which distinct structure?
• What method is used to identify prior exposure to Mycobacterium tuberculosis?
• How much whole blood protection does a full 300 ug dose of RhIg provide?
• What genotype is found most frequently in the Caucasian population?
• Which ketone component is measured by the nitroprusside reaction?
• Which of the following types of molecules is MOST LIKELY to be antigenic/immunogenic?
• The JAK2 mutation is primarily associated with which medical condition?
• What feature is characteristic of Diphyllobothrium latum?
• What is the accepted interval between whole blood donations?
• What is the toxic level of lithium, measured in mmol/L?
• Increased levels of which compound are associated with risk factors for HbS polymerization?
• Which LD isoenzyme is known as LD 3?
• What type of agar is most suitable for isolating enteric gram-negative bacteria?
• In which condition is increased alkaline phosphatase most commonly found?
• Which metallic activator is important for alkaline phosphatase and creatine kinase activity?
• Which type of lipoprotein transports the MAJORITY of cholesterol to cells for steroid hormone synthesis?
• Which condition is monitored using microalbuminuria?
• Which bacteria is known for being indole positive?
• Which infection is commonly linked to a reactive lymphocytosis?
• What is a primary benefit of RPR or VDRL tests?
• What condition might lead to increased levels of leucine, a branched-chain amino acid?
• Uric acid is the final breakdown product of which two purines?
• In newborns, what is the primary risk factor for developing hemolytic disease related to blood type incompatibility?
• Which of the following organisms is commonly tested for with an indole test?
• Which of the following antibiotics is primarily used to treat Gram-negative bacterial infections?
• Starch stains ______________________ with iodine.
• Which cellular structure is commonly seen in severe infections and burns?
• What transferrin level is significant enough to warrant further investigation for hereditary hemochromatosis?
• What test should be performed to determine if the patient has lupus anticoagulant?
• Which bacterial species requires xylene extraction and Ehrlich's reagent for the indole test?
• Which substance conjugates bilirubin for excretion?
• What are the proper storage requirements for granulocyte concentrates?
• At what temperature do Rh antibodies react best?
• Which test is used to confirm the presence of Bence-Jones proteinuria?
• What role does glucuronic acid play in the body?
• Which factors are part of the extrinsic pathway of coagulation?
• Which of the following bacteria are known to be VP positive?
• What technique is used to separate larger DNA fragments?
• Which component is primarily responsible for the viscosity of blood?
• In a heterozygous state for HbS, what other hemoglobin appears alongside HbS in sickle cell trait?
• What is the MOST reliable method for determining the appropriate dosage of Rh immune globulin to give after delivery?
• What is the approximate pH alteration of normal blood in a closed vessel standing at 37C for 1 hour?
• Which amino acid is found in maple syrup urine disease?
• What hazardous material does the blue section of the fire diamond indicate?
• What order of reaction depends solely on enzyme concentration?
• Which method for long-term diabetic monitoring is recommended for patients with sickle cell anemia?
• What is the term for red cells that begin forming enough hemoglobin to be visible on a Wright-stained bone marrow aspirate smear?
• How does Acinetobacter baumannii appear on MAC agar?
• Where does the second hydroxylation of vitamin D take place in the body?
• What signaling molecule's synthesis is prevented by aspirin ingestion in platelets?
• What procedure is typically done last in cases of severe ITP?
• Which two protein bands are confirmed to identify HIV-1 infection in addition to HIV p24?
• Which molecular method uses fluorescent probes to evaluate genes and/or DNA sequences on chromosomes?
• What type of pneumonia is particularly associated with immunocompromised individuals?
• What is the most appropriate specimen type for urine culture?
• U1RNP positivity is associated with which condition?
• Which laboratory test is most useful for evaluating renal function?
• A potential donor who has received a German measles (rubella) vaccine is deferred for how long?
• Which of the following is least likely to interfere with hemoglobin measurements?
• Which laboratory value would most likely be elevated in inflammatory conditions?
• Which dimorphic fungus can produce black, yeast-like colonies after prolonged incubation at 37°C?
• What type of hemolysis is typically observed in hereditary spherocytosis?
• Which species of Aspergillus is characterized by a granular to wooly texture and may appear yellow or yellow-green?
• Which condition is least associated with antibodies directed against granulocyte antigens?
• What coenzyme does lactate dehydrogenase (LD) utilize to convert lactate to pyruvate?
• What formation does Cardiobacterium hominis exhibit?
• What are Alder-Reilly granules primarily composed of?
• Which of the following is NOT considered a reducing sugar?
• Acetest can be used to test for ketones in which of the following?
• Which of the following is true about Lewis antigens?
• What type of cells are characterized as polychromatic normoblasts during the blood formation process?
• What type of organism is Rickettsia classified as?
• Which enzyme is associated with conditions affecting skeletal muscles?
• What dye-binding method uses an increase of absorbance at 595 nm to determine total protein concentration?
• At what temperature should a PT sample be stored until collected by a courier?
• What characteristic distinguishes Klebsiella, Enterobacter, and Serratia from other Enterobacteriaceae?
• Which helminth is characterized by a long buccal cavity in the rhabditiform larval stage?
• Which of the following is a characteristic feature of motile bacteria?
• The antigen marker most closely associated with the transmission of HBV infections is?
• Which organism is described as tiny, weak staining, gram-negative coccobacilli?
• A spectrophotometric scan of amniotic fluid is valuable in diagnosing which condition?
• Which of the following is NOT a common symptom of glomerulonephritis?
• Which selective agar is used for isolating Yersinia enterocolitica?